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Learn the key terms associated with Photoshop (see Table 2-1) and how to use them to filter the information in this book for your needs. A common mistake people make when they first start out is thinking they’re going to be doing image editing on the computer all day. They start out in the wrong field and go out of their way to make it worse. Take your time and enjoy the task you are learning to do.

Table 2-1 A Photoshop Primer: Key Terms and Features

Feature | Summary

— | —

Select/Invert | Select tools make objects in the image visible. Invert tools make objects invisible (they do the opposite of Select tools).

Crop | Cropping is the act of cutting out a portion of an image (a rectangle on the image’s edge).

Levels | Levels is a kind of histogram that can be used to make subtle adjustments to the image or adjust pixels that are out of the normal range.

Mask | A mask is simply a picture that indicates where the image should be visible; it’s an image that surrounds the image and indicates where it can and cannot be visible.

Grain | It can be set to add or reduce the level of blur to an image.

Channels | Channels are the three-color (RGB) color blocks that make up an image: red, green, and blue.

Photoshop enables you to create and use layers. Layers can be stacked on top of each other to add variety to a project. In general, you use Layers when you are creating a project or just designing a project because layers allow you to create several objects in a single file and move them around as needed. Layers allow you to create multiple objects in a single file.

Table 2-2 explains some of the basic principles of layers in Photoshop:

Layers and channels are placed on the top layer of the file. Layers can be moved and changed.

Layers are not permanent unless they’re set to be permanent. When layers are not set to be permanent, any changes to them will be erased when you close Photoshop. You can correct mistakes on a permanent layer or move it down a layer.

You create a layer in Photoshop and use it in a project. Layers can have multiple different layers that are added one after another to create a project.

Layers are an important feature in any good image editing program. Photoshop

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What is Photoshop?

Photoshop is an illustration program that allows users to create and edit images that contain a range of objects: shapes, text, and images.

To shape an object, you select it and use the pen tool to define the shape. Different pen tools will create different kinds of shapes.

You can resize and move shapes by simply clicking a point on the shape and dragging the point, or you can use a “scale” object that gives you a grid on which you drag.

Some shape tools allow you to draw a line or curve based on a graphic object. You can also draw straight lines and curves to connect shapes, such as nodes to a path, or to connect a node to a line.

The area around a shape is called a “region”. You can double-click to select a range of pixels and edit them or you can use a selection tool to drag to select a specific area of the image.

Another way to select pixels is with the selection tool, which looks like a crosshair. When you click anywhere on the image, you’ll see the area of the image that will be “painted” as a result of that click. Use the selection tool to select an object or a specific section of the image. You can then adjust the size of the selection, change its color, invert it, add or subtract a section of the selection, and even replace the background color. You can even specify a different background color for each selection.

You can also copy and paste existing selections in or out of the image. You can draw new selections by clicking the canvas and dragging the cursor.

You can edit the individual pixels or “edit points” of a shape after you’ve defined it. You do this by using the paint bucket tool. If you place the paint bucket tool over an area of the image that isn’t fully black and white, it changes to a color that will reveal areas of the image that aren’t solid black or white. You can change the color by changing the color of the paint bucket.

You can also use the pencil tool and use the eyedropper tool to sample a color from an object in the image.

In Photoshop Elements, you can use the adjustment tools to modify colors, add or remove black and white points, and also sharpen, soften, or blur an image, among other things.

You can place text anywhere you like on an image and move it around
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The Gradient Fill option enables you to visually alter the color of a given layer. You can use this tool to create an abstract image, to fill in a surrounding area of an image, or to create a halo around an object in an image.
Fill lets you apply a flat color to an object in an image. It’s useful for creating an image that has a similar tone to an existing object.

The Pen tool lets you draw letters, numbers, or shapes in an image. The pen can be configured in various ways to highlight certain colors or shapes, and you can adjust the size, opacity, stroke, and other details of the line you draw.

The Selection Brush lets you precisely select objects in an image. You can use the brush to select an object in a photo, fill a selection, and cut, copy, and paste it to another area of an image.
You can crop out a certain area of an image and reduce the size of it. This is particularly useful when you want to place an object in an image that has a smaller area than the image you have chosen.

The Eraser tool lets you remove parts of an image, such as objects or text, that you do not want to use in the current image. The Eraser can be customized to include several types of options, including a fast eraser, a paint bucket, a rubber, and a traceless eraser.

The Blur option adds a blurry effect to an image. You can use this feature to create a dreamy look, to give an image a feeling of depth, or to soften the edges of a face in an image.
The Draw tool lets you trace a line, path, or grid in an image. You can use the Draw tool to draw precise lines for measurements, to mark up a large image, to draw objects for photo retouching, or to draw a pattern for an image that has a background or pattern.

The Pathfinder panel allows you to select which areas of an image should be replaced. Once you have selected an area that you want to copy, you can save time by using the Pathfinder panel to make the rest of the image easier to work with. You can use the path to create nested layers or shapes in an image.

The Layer Masking option enables you to create a variety of effects in an image. For example, you can mask an object in an image to show only a specific color or detail. You can use

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Crystal structure of the human peroxisome proliferator-activated receptor alpha.
The peroxisome proliferator-activated receptor (PPAR) family consists of three members, alpha, beta/delta and gamma, all of which function as ligand-dependent transcription factors. A coactivator molecule (SRC-1 or SRC-2) binds to PPAR in the presence of a ligand, leading to nuclear translocation, receptor dimerization, and gene expression. alpha and gamma PPARs are both able to mediate these responses, whereas beta/delta PPAR has only the transcriptional activity. The crystal structure of the agonist-bound human PPAR alpha (hPPAR alpha) ligand-binding domain (LBD) reveals a six-helix, leucine-rich repeat-like domain (LBD), with the helices connected by loops. The LBD is composed of two separate domains, a N-terminal region, followed by the ligand-binding domain, and a C-terminal region. The structural similarity of the LBDs of PPAR alpha, beta/delta and gamma indicates that their functions are closely related. The carboxylate groups of a glutamate, and the hydroxyl group of a tyrosine in the LBD of PPAR alpha form hydrogen bonds with the ligand, and positively affect the binding affinity. Also, there is a contact between one of the hydroxyl groups and the conserved P-box, which is suggested to be important for transcriptional regulation.Tracheo-oesophageal fistulae (TOF) are common malformations of the upper aerodigestive tract seen in up to 1 in 10,000 births. The incidence of TOF is believed to be rising because of the increased survival of premature infants. The aim of this study was to report the incidence, aetiology and clinical presentation of TOF in our institution.

PATIENTS AND METHODS:

We retrospectively reviewed the medical records of all patients diagnosed with TOF in our institution between 2005 and 2012. Demographic, clinical, surgical and outcome data were recorded.

RESULTS:

Forty-eight children were diagnosed with TOF in this time period; 39 were born at our institution and 9 were referred from another centre. Data for age, gender, birth weight and gestational age were available for 44 of 48 patients. The

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OS: Windows 10, Windows 8/8.1, Windows 7/7 SP1
Processor: Intel Core i3 2.2 GHz / AMD Phenom II X4 945 GHz or better
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DirectX: Version 9.0c
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