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Tekla Structures v19 – Autodesk Reviews – Revit – Autodesk Autocad Steel, aluminum, or timber connectors – custom-made to fit your needs; Tekla Steel, metal and aluminum connectors – solution for use with .Early reinduction chemotherapy with a combination of high-dose methotrexate, cytarabine, and aclarubicin for adult patients with relapsed acute myelogenous leukemia: a report from the Japan Adult Leukemia Study Group.
Since late 1980s, major randomized studies have demonstrated that initial reinduction therapy is essential for treatment of patients with acute myelogenous leukemia (AML) who fail to achieve remission after an initial induction therapy. However, the clinical significance of the timing of reinduction remains unclear. We performed a multicenter, phase II study to investigate the efficacy of reinduction chemotherapy on adult patients with relapsed AML. The study included 143 adult patients who had relapsed in first hematologic remission after having achieved complete remission (CR) after their initial therapy. Patients were assigned to receive the following therapy, HDM+CY+ACLAR (HDM group, n = 71) or HLDM+CY+ACLAR (HLD group, n = 72). The Slot Gacor Gampang Menang rate (complete response [CR] + partial response [PR]) was higher in the HDM group (67%) than in the HLDM group (45%). Patients in the HDM group had a significantly higher overall survival rate (OS) than those in the HLDM group, although the difference was not significant in patients who received HSCT (P =.097). The OS rate at 3 years was 44% and 14% for the HDM group and HLDM group, respectively. The CR/CR with incomplete platelet recovery rate was similar (14% vs 12%, P =.80) in both groups. Patients with refractory AML (n = 18) had a significantly poorer survival in both groups (P
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